Sclerotherapy is a relatively simple spider vein treatment and reticular vein removal procedure using tiny needles to inject a sclerosing solution into the problem veins, causing them to collapse and fade. Not only will the leg’s appearance improve dramatically, but the bothersome symptoms associated with spider veins will also significantly improve, including burning, aching, swelling, and night cramps. Sclerosing agents that are used for reticular and spider vein removal are mild enough to allow predictable and relatively painless treatment.