The LITE study is a randomized, pragmatic (real world) study comparing the effectiveness, tolerability and duration of treatment response through 12 weeks of home vs. office based UVB phototherapy for treatment of psoriasis, conducted by the University of Pennsylvania. Participants will receive a total compensation of $140.

Total duration of study is 24 weeks.

  1. Treatment period: 1-12 weeks
  2. Observation period: weeks 16, 20, 24

Inclusion Criteria

  • Age 12 or older
  • Plaque or guttate psoriasis predominantly located on trunk and/or extremities and is considered a candidate for phototherapy. There is no minimum BSA requirement and patients will be allowed to use concomitant topical and systemic therapy
  • Patient is deemed willing and able to comply with either in-office or in-home phototherapy:
    • In office: Able to travel 2-3 times per week for 12 weeks to one of our offices (patient will be subject to their normal co-pays)
    • In home: Has space to accommodate home phototherapy unit and patient is able to follow home phototherapy instructions (device is loaned to patient at no cost for 12 weeks)

Exclusion Criteria

  • Patients with known history of lack of efficacy to phototherapy or treated with phototherapy 14 days prior to baseline visit.
  • Psoriasis predominantly located on scalp, body folds, genitals, palms and/or soles (areas not amenable to phototherapy)
  • Patients deemed unsafe to be treated with phototherapy (i.e history of invasive melanoma or systemic lupus erythematosus)

For questions and participant referrals, including self-referrals, contact or call 425-275-4404.

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